Glucocorticoids and Transaminase Activity

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Glucocorticoids and Transaminase Activity. Vi. Comparison of the Adaptive Increases of Alanine- and Tyrosine-alpha-ketoglutarate Transaminases.

The activity of alanine-cr-ketoglutarate transaminase (n-alanine :2-oxoglutarate aminotransferase, EC 2.6.1.2) is increased markedly in the livers of diabetic or fasted rats (1). The induction of this enzyme also occurs when either intact or adrenalectomized rats are fed diets high in protein or given corticosteroid injections (24). The adaptive response of this enzyme in glucocorticoid-sensiti...

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Glucocorticoids and Transaminase Activity VI. COMPARISON OF THE ADAPTIVE INCREASES OF ALANINE- AND TYROSINE-(Y-KETOGLUTARATE TRANSAMINASES*

The activity of alanine-cr-ketoglutarate transaminase (n-alanine :2-oxoglutarate aminotransferase, EC 2.6.1.2) is increased markedly in the livers of diabetic or fasted rats (1). The induction of this enzyme also occurs when either intact or adrenalectomized rats are fed diets high in protein or given corticosteroid injections (24). The adaptive response of this enzyme in glucocorticoid-sensiti...

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Transaminase activity in human blood.

Enzymatic transamination consists of the enzyme catalyzed reversible transfer of the alpha amino nitrogen of an amino acid to an alpha-keto acid with the synthesis of a second amino acid and a second alpha-keto acid. Enzymes catalyzing different transamination reactions are found widely distributed in animal tissues and have been shown to change in activity in some tissues during disease (1-3)....

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Transaminase Activity in Neurospora crassa

It is now believed that the amino groups of isoleucine and valine are accepted by their respective carbon chains during biosynthesis via a transamination. Most of the evidence for this hypothesis has been derived from experiments on isoleucineless and valineless mutants of Escherichia coli and Neurospora crassu (l-4). It is not positively established whether this transamination step can be medi...

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Transaminase activity after codeine administration.

THE quantitative and serial changes that occur in serum glutamic-oxaloacetic transaminase (SGOT) activity during the course of a myocardial infarction are well recognized. Changes in SGOT activity have been observed in other diseases such as hepatitis and pancreatitis (Wroblewski and LaDue, '955; Chinsky, Shmagranoff and Sherry, 1956) and after the administration of drugs such as chlorpromazine...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1963

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)75332-0